Last update
6/2/2026
Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.6
Supplement Facts
Serving Size:  1 Capsule
Amount Per Serving
%DV
Magnesium(from 513 mg Buffered Magnesium Glycinate Chelate Complex [Magnesium Oxide and Magnesium Bisglycinate])
200 mg
48%
Magnesium-Rich Plants BlendOrganic Spinach LeafOrganic Chard LeafOrganic Okra FruitOrganic Quinoa Grain (Chenopodium quinoa)Organic Black Bean (Phaseolus vulgaris)Organic Pumpkin SeedOrganic Sunflower SeedOrganic Flaxseed
30 mg
**
📅 Last updated:

Top Medical Research Studies

7
CMT shows potential for pain relief
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
7
Pamidronate therapy reduces bone pain
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.

The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.

Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More

Most Useful Reviews

6
Enhances sleep
One of my favourite brands. Its quality is excellent, and it features natural ingredients. The bright and convenient packaging is a plus. Magnesium is advantageous for bones, joints, muscles, and the nervous system, and I’ve noticed improvements in my sleep. The capsule size and taste are secondary to me; the health benefits are paramount. I consistently take magnesium while occasionally switching brands.
Read More
6
Nerve calming effect
6 people found this helpful
I found this product calming and it helps with relaxation. Although I expected to sleep better, that didn’t happen. However, I appreciate its ability to soothe my nerves and aid my joints and bones, so I plan to repurchase it.
Read More
6
Relieves insomnia
Very effective for alleviating insomnia and healing bone pain.
Read More

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Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
  • All Researches
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.

Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
7
Pamidronate therapy reduces bone pain
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.

The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
CMT shows potential for pain relief
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 4 Reviews
7.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
6
Enhances sleep
One of my favourite brands. Its quality is excellent, and it features natural ingredients. The bright and convenient packaging is a plus. Magnesium is advantageous for bones, joints, muscles, and the nervous system, and I’ve noticed improvements in my sleep. The capsule size and taste are secondary to me; the health benefits are paramount. I consistently take magnesium while occasionally switching brands.
Read More
6
Nerve calming effect
6 people found this helpful
I found this product calming and it helps with relaxation. Although I expected to sleep better, that didn’t happen. However, I appreciate its ability to soothe my nerves and aid my joints and bones, so I plan to repurchase it.
Read More
6
Relieves insomnia
Very effective for alleviating insomnia and healing bone pain.
Read More
2
Weakens bone pain
Magnesium is excellent for combating weakness in the body and bones, especially when taken before bed. Generally, this company provides excellent products.
Read More

Frequently Asked Questions

7
CMT shows potential for pain relief
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.

Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.

References

  1. Alsaikhan F, Mahmoud MZ, Suliman M. Synthesis and characterization of novel denosumab/magnesium-based metal organic frameworks nanocomposite prepared by ultrasonic route as drug delivery system for the treatment of osteoporosis. Front Bioeng Biotechnol. 2023;11:1153969. 10.3389/fbioe.2023.1153969
  2. Jakubowska-Pietkiewicz E, Chlebna-Sokół D. New trends in the treatment of osteogenesis imperfecta type III - own experience. Ortop Traumatol Rehabil. 2008;10:593. PubMed
  3. Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129. PubMed
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